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Nanotoxicology “focuses on determining the adverse effects of nanomaterials on human health and the environment.”

When manufacturers add titanium dioxide to foods and other ingestible products, it’s typically referred to as E171, which relates to food-grade purity.

Titanium dioxide can be both safe and unsafe, depending on its use. When inhaled, titanium dioxide is considered possibly carcinogenic to humans. This means that in products that contain powdered titanium dioxide like loose powders, pressed powders, eyeshadows, and blushes in which the makeup is in powder form, titanium dioxide can be inhaled. Titanium dioxide is also an occupational chemical of concern, as workers might inhale titanium dioxide when manufacturing products.